Prophylactic Application of an Intra-Aortic Balloon Pump in High-Risk Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

Background: An intra-aortic balloon pump (IABP) is the most commonly used circulatory assist device in cardiac surgery. We hypothesized that prophylactic application of an IABP improves early clinical outcome of high-risk patients undergoing scheduled off-pump coronary artery bypass grafting (OPCABG). Methods: From January 2010 to December 2013, hemodynamically stable, high-risk patients undergoing scheduled OPCABG with preincision use of an IABP were recruited to the IABP group. Using the propensity score-matching method, every patient in the IABP group was matched with another patient (the control group) with a similar propensity score who received an IABP on an asneeded basis during or after OPCABG. Surgical mortality and major morbidity rates were compared between groups. Results: A total of 116 patient pairs were included in this study. In patients in the IABP group, postoperative low cardiac output and respiratory as well as renal failure were less frequent, Received: August 22, 2014 Accepted after revision: February 4, 2015 Published online: April 18, 2015 Qiang Ji, MD, PhD Department of Thoracic Cardiovascular Surgery Tongji Hospital, Tongji University 389 Xincun Road, Shanghai 200065 (PR China) E-Mail drjiqiang @ tongji.edu.cn ChunSheng Wang, MD, PhD Department of Cardiovascular Surgery Zhongshan Hospital, Fudan University 180 Fenglin Road, Shanghai 200032 (PR China) E-Mail wang_chunsheng @ zs-hospital.sh.cn © 2015 S. Karger AG, Basel 0008–6312/15/1312–0109$39.50/0 www.karger.com/crd W.D. and Q.J. contributed equally to this work. Th is is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only. D ow nl oa de d by : 54 .7 0. 40 .1 1 11 /2 0/ 20 17 2 :5 0: 11 A M